Day 2 :
Pontifical Catholic University of Parana, Brazil
Gustavo Gomes de Castro Soares completed his higher education from Pontifical Catholic University of Parana, Brazil and his interest in Sporulated Bacillus as alternative treatment for diarrhea of hospitalized adult patients under enteral nutrition: A pilot randomized controlled study
Since it is multifactorial, the treatment of diarrhea in hospitalized patients undergoing enteral nutrition is a constant challenge for clinicians. The use of probiotics to treat diarrhea has been investigated for long term. The B cereus was shown to have antibiotic efficacy on several pathogenic bacteria in humans. It was also effective in treating intestinal gastroenteritis associated to antibiotics. In a recently published study of our group, we have tested the use of a single probiotic strain, B. cereus, compared to a fiber mix in the treatment of diarrhea of ICU patients on enteral nutrition. The use of soluble fibers has been accepted as an effective way to treat diarrhea of patients on enteral nutrition. In former probiotic studies, the period of five days was effective in diarrhea treatment. We have studied 58 patients, 29 on fiber and 29 on B. cereus treatment. All the other factors were similar. In number of patients, the cessation of diarrhea was similar in both groups. However, compared to fiber, the probiotic group was effective earlier (two days). Another interesting data was that specifically malnourished patients had a better response on diarrhea cessation on probiotic treatment. Our study opens a new research segment. There are questions which should be answered in future, such as the effect of a combination of fiber and B. cereus in the treatment of diarrhea. And the specific effects in patients with different malnutrition degrees. Also, B. cereus could be compared to another single probiotic, with the same dosage, in the treatment of diarrhea of ICU malnourished patients on enteral nutrition
Iran University of Medical Sciences, Iran
Keynote: Dietary intervention and reducing the side effects of chemotherapy among women with breast cancer
Time : 11:05-11:50
Mitra Zarrati completed her PhD years from Tehran University of Medical Sciences. She is the Director of Nutrition Sience. Her researches published more than 14 papers in reputed journals and has been serving as an editorial board member of repute.
Objective: Gastrointestinal (GI) side effects caused by chemotherapy in women with breast cancer are common but poorly understood which might be controlled by nutritional intervention; thus, the major aim of this study was to assess the effect of dietary intervention along with nutritional education on reducing these side effects.
Methods: The present study is a single-center, single-controlled and randomized trial, a total of 150 patients with breast cancer undergoing chemotherapy were randomly assigned into intervention groups to receive dietary intervention and nutritional education (n=73) or control group (n=67), after their three sessions of chemotherapy for 10 weeks. The primary endpoint was the GI symptoms after each session of chemotherapy that were measured by a designed questionnaire based on ROME III questionnaire.
Results: The severity of GI side effects in the dietary intervention along with nutritional education was decreased significantly in the third session of chemotherapy compared to the first session, which included reflux disorder (P=0.05), anorexia (P<0.001), nausea (P=0.002), constipation (P<0.001) and diarrhea (P<0.001); moreover, significant reductions were observed in the severity of GI side effects in the intervention group compared to control group after the third session (P<0.001). After adjusting the analysis for baseline values including age, job, education level, weight and body mass index, significant changes were observed for GI side effects in the intervention group compared to the control group (P<0.001).
Conclusions: This study showed beneficial effects of individualized dietary intervention along with nutritional education on reducing diarrhea, constipation, vomiting and nausea in women with breast cancer during the chemotherapy
Maharshi Dayanand Saraswati University, India
Ritu Mathur has been teaching Nutrition in the Department of Food Science and Nutrition at the MDS University, Ajmer since the last 23 years. She did her Ph.D. from University of Rajasthan, Jaipur with scholarship (Junior and Senior research Fellowship) from the University Grants Commission, New Delhi. She secured first position and Gold Medal both at the B.Sc. and M.Sc. level. She has participated in various National and International Conferences and seminars, presented papers and chaired scientific sessions, won several best paper awards, published more than 25 research papers in indexed and reputed National and International journals with a very good Google scholar citation, i-10 and h - index.
Cardiovascular disease (CVD) is a group of heterogeneous and interrelated diseases which include coronary heart disease, ischemic heart disease, peripheral vascular disease, atherosclerosis, hypertension and heart failure. These diseases are interrelated and often coexist. CVD remains the number one killer of both men and women in many countries across the world including India. Myocardial infarction or ischemia in one or more of the coronary arteries with tissue damage is the main form of heart disease responsible for CVD deaths. Atherosclerosis is the chronic, local inflammatory response to risk factors such as high levels of low density lipoprotein cholesterol. The other major risk factors include hypertension, age, diabetes mellitus, micro albuminuria, family history of premature CVD, elevated triglyceride levels, low HDL levels, inflammatory markers, fibrinogen, C-reactive protein, elevated levels of Homocystiene and Lipoprotein a, tobacco, stress, faulty diet, insufficient sleep, obesity, physical inactivity, hypertension and metabolic syndrome (frequently seen in Indians). Therapeutic life style changes, medical interventions and nutritional management can prove to be the cornerstone both in the prevention and treatment of CVD. Education and awareness in this regard is the need of the hour to save millions of people around the world from dying from this disease which is the world’s number one killer disease of the 21st century