Nassima Malti is a researcher at Laboratory of Physiology and Biochemistry of Nutrition, Department of Biology, Faculty of Sciences, University of Tlemcen. She has completed his PhD at in 2014.
Obesity is considered a risk factor during pregnancy and influences the development of obesity and its complications in adulthood during pregnancy (maternal, fetal or placental). Besides eating disorders and obstetric complications, obese mothers have a high incidence of oxidative disorders. Oxidative stress, characterized by an increase in free radical activity and a reduction in antioxidant defenses, is a common feature between metabolic and physiological disorders of obesity and those of pregnancy. It becomes a very important risk factor to consider in obese pregnant women. In addition, obesity is associated with an inflammatory state characterized by hyperleptinemia which plays a major role in the pathophysiology of insulin resistance. Leptin inhibits insulin secretion in the β-cell; there is a feedback loop, called the adipo-insular axis, where insulin increases the secretion of leptin which, in response, inhibits insulin secretion. A possible leptino-resistance, in which the loop is disturbed, would be responsible for hyperleptinemia and hyperinsulinemia observed in diabetes.\r\nThe aim of this study is to evaluate the correlation between maternal leptin and some markers of erythrocyte oxidative status (nitric oxide, superoxide anion, malondialdehyde, carbonylated proteins) during pregestational obesity.This work is part of a study on the assessment of redox status during maternal obesity and its alterations on foeto-placental unit\r\n
Maria Papamichael is a registered dietician who has dedicated her life in educating people the importance of good nutrition and exercise in the prevention and management of disease as well as in improving health and well-being. Being an asthma sufferer since childhood, has motivated her to undertake a PhD research project at La Trobe University to investigate the prophylactic potential of a Mediterranean diet enriched with fatty fish in the management of asthma in children.
Asthma is an inflammatory disease in the lungs which over the past thirty years has escalated in children. Considerable interest exists in the therapeutic potential of dietary omega 3 fatty acids, due to anti-inflammatory and immune-modulating effects on asthma. However, studies performed to date are inconclusive and this requires further exploration.\r\nThis six month Randomized Controlled Trial aims to investigate whether fatty fish as part of the Greek Mediterranean diet reduces asthma symptoms in children. A sample of 64 children will be recruited from a paediatric asthma clinic in Athens, Greece. Participant children will be randomized into two groups. The intervention group is required to consume two meals of fatty fish (≥150gr cooked fish) per week over a period of 6 months in the context of the Greek Mediterranean diet. The control group will consume their usual diet. Outcome measures will be assessed at base-line and at the end of six months. Questionnaires will be used to collect socio-demographics data, medical information, dietary habits, asthma control and quality of life details. Pulmonary function will be assessed using spirometry and exhaled nitric oxide. In addition, blood and urine tests will be examined to assess patient’s metabolic profile, antioxidant status, plasma fatty acid composition and Vitamin D. \r\nThis study intends to establish whether fatty fish consumption can be used as an adjunct therapy in the management of asthma in children\r\n